Biomicroscopia Ultrassônica - Um aliado no diagnóstico da metástase no melanoma - estudo em animais
DOI:
https://doi.org/10.29384/rbfm.2015.v9.n3.p10-14Abstract
O melanoma é o tipo mais agressivo de câncer de pele. A agressividade no melanoma se caracteriza por sua capacidade metastática, e esta agressividade está diretamente relacionada ao diagnóstico tardio. A técnica utilizada neste trabalho foi a biomicroscopia ultrassônica (BMU) – ultrassom de alta frequência - com o objetivo de diagnosticar, de forma não invasiva, em tempo real, o processo de metástase das células de melanoma do tumor primário para o linfonodo sentinela (LFS), em um estudo longitudinal. Neste estudo observou-se fenômenos biológicos ao longo do tempo, como a angiogênese, migração e invasão das células de melanoma no LFS. Concluímos que a BMU pode ser uma útil ferramenta, oferecendo antes da biópsia do LFS, relevantes informações quanto à metástase, possibilitando o início precoce do tratamento, podendo aumentar significativamente a sobrevida do paciente.
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