Study on the location of punctual breast density in different thicknesses of the compressed breast
DOI:
https://doi.org/10.29384/rbfm.2023.v17.19849001703Keywords:
global breast density, punctual breast density, screening mammogramAbstract
Breast density, defined as the percentage of fibroglandular tissue in the breast, has the potential to be used as a predictor of breast cancer risk. Recent studies indicate that the maximum punctual breast density, which is an underexplored measure and is a factor that has a greater link with breast cancer than the global breast density, the latter is the most used to measure the breast density. This study aims to identify whether the breast point density of 1cm2 of area is located in different regions of the breast in the different compressed breast thicknesses (CBT). In this retrospective study, mammographic images were analyzed in the medial-lateral oblique (MLO) and craniocaudal (CC) projections of 1192 women aged between 25 and 89 years and CBT between 30 and 89 mm. The information used was: CBT (mm), the distances from the posterior, superior and medial edges of the breast, (DPEB) (mm), (DSEB) (mm), and (DMEB) (mm), respectively, up to the location of the 1 cm2 of the maximum breast density punctual (MBDP), the volumetric density of the global breast (VDGB) (%), the MBDP (1 cm2) and the volume of the breast (cm3). The results of this study show that MBDP follows the same behavior as VDGB, in relation to the influence of CBT. Regarding the location of the MBDP, there is little evidence that CBT is a factor of strong influence.
Downloads
References
BRAY, F.; FERLAY, J.; SOERJOMATARAM, I.; SIEGEL, R.L.; TORRE, L.A; JEMAL, A. Global cancer statistics. GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians, Hoboken, V. 68, p. 394-424, 2018.
FERLAY, J.; ERVIK, M.; LAM, F.; COLOMBET, M.; MERY, L.; PIÑEROS, M.; ZNAOR, A.; SOERJOMATARAM, I.; BRAY, F. [online]. Global Cancer Observatory: Cancer Today. Lyon, France. (2018).
GØTZSCHE, P.C.; JORGENSEN, K.J. Screening for Breast Cancer with Mammography. Cochrane Database of Systematic Reviews, v. 6, p. CD001877, 2013.
IARC - International Agency for Research on Cancer. Breast Cancer Screening. International Agency for Research on Cancer Handbooks of Cancer Prevention, .2016.
MCCORMACK, V.A.; DOS SANTOS SILVA, I. Breast density and parenchymal patterns as markers of breast cancer risk: a meta-analysis. Cancer Epidemiology Biomarkers, v. 15, p. 1159-69, 2006.
PEREIRA, S.M.P.; MCCORMACK, V.A.; HIPWELL, J.H.; RECORD, C.; WILKINSON, L.S.; MOSS, S.M.; HAWKES, D.J.; SILVA, I.S.; Localized Fibroglandular Tissue as a Predictor of Future Tumor Location within the Breast. Cancer Epidemiology Biomarkers. V. 20, p. 1718-25, 2011.
NAZARI, S. S.; MUKHERJEE, P. An overview of mammographic density and its association with breast cancer. Breast Cancer, v. 25, n. 3, p. 259–267, 2018.
VINNICOMBE, S.J. Breast density: why all the fuss?. Clin. Radiol. V. 73, p. 334–357, 2017.
ALI, M.A.; CZENE, K.; ERIKSSON, L.; HALL, P.; HUMPHREYS, K. Breast tissue organization and its association with breast cancer risk. Breast Cancer Res., v. 19, p. 103, 2017.
HOLLAND, K.; GILS, C.H.V.; MANN, R.M.; KARSSEMEIJER, N. Quantification of masking risk in screening mammography with volumetric breast density maps. Breast Cancer Res Treat., v. 162, p. 541-548, 2017.
ZULFIQAR, M.; RAHMAH, M. Do the majority of Malaysian women have dense breasts on mammogram? Biomedical imaging and intervention journal, v. 7, p. e14, 2011.
ZOETELIEF, J.; VELDKAMP, W.J.H.; THIJSSEN, M.A.O.; JANSEN, J.T.M. Glandularity and mean glandular dose determined for individual women at four regional breast cancer screening units in The Netherlands. Phys Med Biol, v. 51, p. 1807–17, 2006
MOSHINA, N.; ROMAN, M.; WAADE, G.G.; SEBUODEGARD, S. Breast compression parameters and mammographic density in the Norwegian breast cancer screening programme. Eur Radiol., v. 28, p. 1662–72, 2018.
CONANT, E. F. et al. Five consecutive years of screening with digital breast tomosynthesis: Outcomes by screening year and round. Radiology, v. 295, n. 2, p. 285–293, 2020.
MOSHINA, N.; ROMAN, M.; WAADE, G.G.; SEBUODEGARD, S. Breast compression parameters and mammographic density in the Norwegian breast cancer screening programme. Eur Radiol., v. 28, p. 1662–72, 2018.
ZOETELIEF, J; VELDKAMP, W.J.H.; THIJSSEN, M.A.O.; JANSEN, J.T.M. Glandularity and mean glandular dose determined for individual women at four regional breast cancer screening units in The Netherlands. Phys Med Biol. v. 51, p.1807–17, 2006.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 CAMILA ENGLER, Maria do Socorro Nogueira, Danielle Soares Gomes
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The submission of original articles to the Brazilian Journal of Medical Physics implies the transfer, by the authors, of the rights of print and digital publication. Copyright for published articles remains with the author, with journal rights on first publication. Authors may only use the same results in other publications by clearly indicating this journal as the original publisher. As we are an open access journal, free use of articles in educational, scientific, non-commercial applications is allowed, as long as the source is cited.
The Brazilian Journal of Medical Physics is under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0).