Dosimetric study in Volumetric Modulated Arc Therapy (VMAT) Technique for patients diagnosed with NSCLC and Its comparison with 3D Conformal Radiotherapy (3DCRT) and Intensity Modulated Radiation Therapy (IMRT)
DOI:
https://doi.org/10.29384/rbfm.2023.v17.19849001664Keywords:
NSCLC, CENTRAL LUNG CANCER, 3DCRT, IMRT, VMAT, CI, HIAbstract
This dosimetric study is based on the VMAT treatment technique in patients diagnosed with Non-Small Cell Lung Cancer (NSCLC) of the central and peripheral lung area. 25 Computed Tomography (CT) scans of adult patients between 35 and 83 years old were used, who previously received external beam radiotherapy (EBT) at Centro Médico Docente La Trinidad (CMDLT). The patients were simulated in the supine position with their arms above their heads. The delimitation of the Planned Tumor Volume (PTV) and the Organs at Risk (OAR) was performed in each patient, a treatment plan was also designed with 3D-CRT using APPA fields + 2 oblique and opposing fields, a plan with IMRT- SW using 7 fields and a VMAT plan with 2 complete arches, then the dosimetric evaluation of the structures involved was performed, a statistical analysis was applied between the implemented techniques and a dosimetric verification was carried out as well as an intercomparison with other articles, finding the most suitable treatment technique for NSCLC placed in the central lung area.
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NATIONAL CANCER INSTITUTE, 2016, recuperado desde: https://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq, Shady Grove Campus Rockville, Non-Small Cell Lung Cancer. USA : COPYRIGHT © ABTA.
Asociación Española Contra el Cáncer AECC, 2017, desde: https://www.aecc.es/SobreElCancer/CancerPorLocalizacion/cancerdepulmon/, tomado del 2017; Tipos de cáncer de pulmón. Madrid.
Ministerio del Poder Popular para la Salud. República Bolivariana de Venezuela Anuario de Mortalidad 2012. Caracas: Ministerio del Poder Popular para la Salud, 2014. 491 05 diciembre 2014.
Organización Mundial de la Salud (OMS), 2014, recuperado desde: http://www.who.int/features/factfiles/cancer/es/; datos sobre el cáncer 2012. s.l.
Hyuna Sung PhD, Jacques Ferlay MSc y colaboradores. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries, CA CANCER J CLIN 2021;71:209–249. doi: 10.3322/caac.21660. Available online at cacancerjournal.com
VALAKH VLADIMIR, y colaboradores. Early-stage Central Lung Cancer and Volumetric Modulated Arc Therapy: A Dosimetric Case Study with Literature Review. Philadelphia, PA, U.S.A.: ANTICANCER RESEARCH , 2013. 33: 4491-4496 (2013).
J.L. Steber et al, Clinical Application of a Hybrid Volumetric Arc Therapy Technique for Locally Advanced Lung Cancer, POSTER VIEWING ABSTRACT| VOLUME 93, ISSUE 3, SUPPLEMENT , E595, INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY, ASTRO, NOVEMBER 01, 2015.
Baker Sarah, Max Dahele2, Frank J. Lagerwaard, Suresh Senan. A critical review of recent developments in radiotherapy for non-small cell lung cancer. s.l. : DOI 10.1186/s13014-016-0693-8, 2016.
Rodriguez Leones, Mariangel Del Carmen. Desarrollo de un protocolo para la irradiación cráneo-espinal en pacientes con meduloblastoma empleando arcoterapia volumétrica modulada. Caracas, CEA - IVIC, 2018.
Kong FM, Machtay M, Bradley J, Ten Haken R, Xiao Y, Matuszak M, et al. RTOG 1106/ACRIN 6697: Randomized phase II Trial of Individualized Adaptive Radiotherapy Using During Treatment FDG-PET/CT and Modern Technology in Locally Advanced Non-Small Lung Cancer (NSCLC). Philadelphia, PA: Radiation Therapy Oncology Group (2012).
Lee Nancy, y colaboradores. Target Volume Delineation for Conformal and Intensity-Modulated Radiation Therapy. Switzerland, © Springer International Publishing Switzerland 2015, 2015.
Morgan-Fletcher, S., 2001. Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50), ICRU Report 62 . ICRU, pp. ix+52, 1999 (ICRU Bethesda, MD) ISBN 0-913394-61-0. BJR, 74(879), pp.294-294.
Chan Clara MD, y colaboradores. Intensity-Modulated Radiotherapy for Lung Cancer: Current Status and Future Developments. s.l. : Journal of Thoracic Oncology, 2014. Volume 9, Issue 11, November 2014, Pages 1598-1608 https://doi.org/10.1097/JTO.0000000000000346.
Perez C.A. y colaboradores. Impact of radiation technique and tumor extent on tumor control and survival of patients with unresectable non-oat cell carcinoma of the lung Report by the RTOG 73-01. Cancer. 1982; 50: 1091-1099.
Emami B, y colaboradores. Tolerance of Normal Tissue to Therapeutic Radiation. Illinois: Reports of Radiotherapy and Oncology, 2013. Vol.1 No.1 Spring 2013.
Urdaneta Nelson, y colaboradores. RADIOTERAPIA ONCOLÓGICA: enfoque multidisciplinario. Caracas: Copyright © MMIX DISINLIMED, C.A., 2009. 2da Edición.
Loïc Feuvret, Georges Noël, Jean-Jacques Mazeron, Pierre Bey, Conformity index: A review, International Journal of Radiation Oncology*Biology*Physics, Volume 64, Issue 2, 2006, Pages 333-342, ISSN 0360-3016, https://doi.org/10.1016/j.ijrobp.20.
ICRU REPORT No. 83. PRESCRIBING, RECORDING AND REPORTING PHOTON-BEAM INTENSITY-MODULATED RADIATION THERAPY (IMRT). s.l. : Published by Oxford University Press, 2010. Journal of the ICRU Volume 10 No 1 2010.
Hammer, Harper, DAT, Ryan, P.D. PAST: Paleontological Statistics Software Package for Education and Data Analysis. s.l. folk.uio.no/ohammer/past, 2001.
Ozawa Takesumi, y colaboradores. Dosimetric Comparisons of Volumetric Modulated Arc Therapy with Three - Dimensional Conformal Radiation Therapy for Locally Advanced Non-Small Cell Lung Cancer. Shinshu : Shinshu Med J, 65⑵:93~98, 2017, 2017.
LI YI, y colaboradores. Dosimetric comparison between IMRT and VMAT in irradiation for peripheral and central lung cancer. Shaanxi : ONCOLOGY LETTERS 15: 3735-3745, 2018, 2018.
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